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. 2016 May 26;11(5):e0156207. doi: 10.1371/journal.pone.0156207

Table 1. Characteristics of the Whole Population.

Factors No LNM (n = 1108) LNM (n = 61) P-value*
% (n) % (n)
Age (mean±SD) 52.9 ± 10.9 50.0 ± 10.8 0.482
Sex (male:female) 611: 497 23: 38 0.007
Tumor location
Upper 9.2 (102) 9.8 (6) 0.720
Middle 44.3 (491) 44.3 (27) 0.560
Lower 46.5 (515) 45.9 (28)
Macroscopic type
Elevated 2.2 (24) 0.0 (0) 0.984
Flat 19.2 (213) 13.1 (8) 0.766
Depressed 52.8 (585) 54.1 (33)
Mixed 25.8 (286) 32.8 (20) 0.276
Ulcer 0.909
No 6.1(1047) 93.8 (57)
Yes 93.9 (61) 6.2 (4)
Tumor size 3.0 ± 2.0 4.2 ± 2.5 0.001
Depth of invasion 0.025
Lamina propria 34.9 (387) 13.1 (8)
Muscularis mucosa 65.1 (721) 86.9 (53)
Number of resected nodes (mean±SD) 40.4 ± 13.7 44.5 ± 14.2 0.059
LVI 0.006
No 97.7 (1083) 80.3 (49)
Yes 2.3 (25) 19.7 (12)

*By logistic regression analysis. LNM indicates lymph node metastasis; SD, standard deviation; EGC, early gastric cancer; EMR, endoscopic mucosal resection; ESD, endoscopic submucosal dissection; LVI, lymphatic-vascular involvement.