Table 2. Summary of studies on size of tissue cysts in the brains of rodents inoculated with T. gondii.
Host | T. gondii strain | Tissue cyst data | References | ||||||
---|---|---|---|---|---|---|---|---|---|
Host | Strain | Sex | No. | P.I. | Methods | No. measured | Size | ||
Mice | BALB/c | M | 5 | aME49 | 1, 2, 6 mo | Brains fixed, cryosectioned, FITC-DB | NS | 1 mo-7-20 μm,2 mo-3-30 μm,6 mo-5-25 μm | [28] |
Mice | STR, Outbred, albino | NS | 18 | bSRRA | 3, 6, 12, 18, 22 mo | Brains fixed, 1 μm sections stained | 3 mo-15-30 μm,6 mo-20-50 μm,12-22-30-50 μm | [29] | |
Mice | NS | 20 | cBurk | 4, 8, 12, 16 and 24 weeks | Brain homogenate in saline | 100 at each time point | 8 weeks-38 μm,12 weeks-40 μm,16 weeks-41 μm,24 weeks-42 μm | [30] | |
Mice | CBA/J | F | 10 | ME49 | 3,4,5,6,8 weeks | Percoll isolated tissue cysts | 630 | Tissue cyst size relatively constant at 5 points studied | [31] |
Rat | Sprague-Dawley | F | 35 | dVEG | 75 days | Brain, formalin fixed, histological sections, HE stain | 224 | Up to 50 μm, most 22.5 to 30 μm | [32] |
a Type II, 200 tachyzoites, subcutaneously.
b Beverley strain from rabbit, genotype unknown, 12 tissue cysts, subcutaneously.
c Genotype unknown, tissue cysts, subcutaneously.
d Type III, 1–1 million oocysts, orally.
M = Male, F = Female, NS = Not stated, mo = Month, P.I. = Post infection.