Table 3. Experimental toxoplasmosis in ratsa inoculated orally with oocysts of 11 strains of T. gondii of different genotypes.
T. gondii strain (Group no.) | ToxoDB PCR-RFLP genotype # (Conventional) | Origin Country | Host | References | No. of oocystse | Died | Day killed | Rat nos. |
---|---|---|---|---|---|---|---|---|
GT1 (1, 2) | #10 (Type I) | USA | Goat | [43] | 100000 | 8/10b | 65 | 6157,6158 |
(52) | 1000 | 0/5 | 62 | 6228–6232 | ||||
TgCtCO2 (3, 4) | #28 (Atypical) | Colombia | Cat | [44] | 100000 | 5/10 | 62 | 6159–6163 |
(53) | 1000 | 0/5 | 66 | 6233–6237 | ||||
ME49 (5, 6) | #1 (Type II) | USA | Sheep | [45] | 10000 | 0/10 | 62 | 6164–6173 |
TgNmBr1 (7, 8) | #1 (Type II) | Brazil | Rabbit | [46] | 100000 | 0/10 | 65 | 7174–6183 |
VEG (9, 10) | #2 (Type III) | USA | Human | [47,48] | 100000 | 0/10 | 63 | 6184–6193 |
TgGoatUS4 (11, 12) | #2 (Type III) | USA | Goat | [49] | 100000 | 6/10 | 63 | 6194–6197 |
(54) | 10 | 0/5 | 62 | 6243–6247 | ||||
TgBbUS1 (13, 14) | #147 (Atypical) | USA | Black bear | [50] | 100000 | 0/5 | 66 | 6243–6247 |
(56) | 1000 | 1/5 c(day 10) | 62 | 6248–6252 | ||||
(55) | 100 | 0/5d | 62 | 6243–6252 | ||||
TgPigUS15 (15, 16) | #8 (Atypical) | USA | Pig | [51,52] | 10000 | |||
TgRabbitBr1(17, 18) | #19 (Atypical) | Brazil | Rabbit | [46] | 10000 | 10/10 | 6144 (day 7) | |
100 | 0/5 | 62 | 6258–6263 | |||||
10 | 0/5 | 62 | 6253–6267 | |||||
TgCtPRC3 (19, 20) | #18 (Atypical) | China | Cat | [53] | 0/10 | 66 | 6208–6217 | |
CT1 (59) | #10 (Type I) | USA | Cattle | [54] | 10000 | D6268-6272 | ||
(60) | 1000 | D6263-6267 |
a All rats were 46 day old on day of T. gondii inoculation.
b Medicated with sulfadiazine I drinking water day 7–10 p.i.
c Medicated with sulfadiazine I drinking water day 10–11 p.i.
d Medicated with sulfadiazine I drinking water day 15–19 p.i.
e Mouse infective units, not actual count.