Table 2.

Bivariate analysis of neonates with moderate-severe encephalopathy treated with whole-body hypothermia within 6 h of birth comparing demographics based on the presence of histologic chorioamnionitis

	With histologic chorioamnionitis (n = 16)	Without histologic chorioamnionitis (n = 34)	P-value
Clinical chorioamnionitis	8 (50%)	2 (5.9%)	0.01a
Maternal age, yearsb	28.8 ± 7.8	25.9 ± 6.9	0.20
Nulliparous	9 (56.25%)	17 (50%)	0.68
Race			0.03a
Caucasian	0	11 (32.5%)
African-American	12 (75%)	14 (41.2%)
Hispanic	3 (18.8%)	6 (17.7%)
Other	1 (6.3%)	3 (8.8%)
Cesarean delivery	10 (62.5%)	27 (79.4%)	0.20
Oxytocin use during labor	7 (43.8%)	13 (38.2%)	0.71
Preeclampsia	3 (18.8%)	4 (11.8%)	0.50
Meconium stained fluid	9 (56.3%)	11 (32.4%)	0.11
Intrauterine growth restriction	2 (12.5%)	2 (5.9%)	0.42
Placental abruption	1 (6.7%)	4 (13.3%)	0.28
Sentinel event	5 (33.3%)	16 (47.1%)	0.29
Nonreassuring FHR tracing	9 (56.3%)	26 (76.5%)	0.15
Male gender	12 (75%)	21 (61.8%)	0.36
5 Min APGAR < 7	12 (75%)	25 (73.5%)	0.91
Length of NICU stay (days)b	14.6 ± 7.6	13.20 ± 9.3	0.59
Neonatal demise	1 (6.3%)	1 (2.9%)	0.58
Intraventricular hemorrhage	2 (13.3%)	2 (6.7%)	0.59
Seizure activity	5 (31.3%)	6 (17.7%)	0.28
Histologic placental infarcts	1 (6.3%)	5 (14.7%)	0.39
Histologic funisitis	10 (62.5%)	0	< 0.01a
Neonatal bacteremia	3 (18.8%)	1 (2.9%)	0.05a

Abbreviations: FHR, fetal heart rate; NICU, neonatal intensive care unit.

^aP < 0.05.

^bMean ± standard deviation.