Fig. 2.

Engagement of CD22 with epratuzumab has no effect on CD22 Tyr⁸²² and Tyr⁸⁴² phosphorylation in tonsil-derived B cells. CD22 was immunoprecipitated from tonsil derived B cells following the treatment and methods described in the legend to Fig. 1. The samples were immunoblotted and probed using specific anti-phospho Tyr antibodies. To ensure equal protein loading an anti-CD22 blot was also carried out