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Effects of emodin on the expression of genes that regulate macrophage activation. A and B, heat maps showing the expression of genes associated with the most significantly affected macrophage canonical signaling pathways. Right panels, the -fold changes of genes caused by LPS/IFNγ or IL4 treatment compared with control (Con) and emodin (Em) treatment compared with LPS/IFN or IL4 for select macrophage activation genes.
