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Dissociation constants of αvβ8 integrin and its swap mutants towards latent TGF-β1
| β-Chains | Kda |
|---|---|
| nm | |
| β8 | 2.3 ± 0.2 |
| β3 | NDb |
| β3–8BI/HYB | 3.3 ± 0.5 |
| β3–8BI | 18 ± 1 |
| β8–3BI | ND |
| β3–8DLL | ND |
| β8–3DLL | 4.7 ± 1.2 |
a Values represent the means ± S.D. of three independent experiments.
b ND means not determined. The dissociation constant was not determined because of the partial saturation only being evaluated at the highest integrin concentration.
