TABLE 1.
Summary of two-hybrid screening results
| Description | Gene name | Accession no. | Protein function | No. of clones | Interaction with SUMO pathway |
|---|---|---|---|---|---|
| Chromodomain helicase DNA-binding protein 3 | CHD3 | Q12873 | ATP-dependent DNA helicase in NuRD complex | 10 | Interacts with SUMOylated proteins |
| RAN-binding protein 9 | RANBP9 | Q96S59 | RAN-binding protein, adaptor protein | 5 | Interacts with SUMO-Ubc9 complex |
| Zinc finger prortein 451 | ZNF451 | Q9Y4E5 | Coactivator of steroid receptors | 4 | Interacts with SUMO-Ubc9 complex |
| Tyrosyl-DNA phosphodiesterase 2 | TDP2 | O95551 | DNA repair enzyme | 3 | Interacts with SUMO-1 |
| Zinc fingers and homeoboxes 1 | ZHX1 | Q9UKY1 | Transcriptional repressor, DNMT3B-mediated | 3 | Conjugated with SUMO proteins |
| Ubiquitin-conjugating enzyme E2I | UBE2I | P63279 | SUMO-conjugating enzyme, homologous to yeast Ubc9 | 1 | SUMO E2 enzyme |
| Chromobox homolog 4 | CBX4 | O00257 | Component of a PcG multiprotein PRC1-like complex | 1 | SUMO E3 enzyme |
| Protein inhibitor of activated STAT1 | PIAS1 | O75925 | SUMO E3 ligase | 1 | SUMO E3 enzyme |