Table 1. Associations between miR-211 expression levels and clinicopathologic features of HCC patients.
| Clinicopathologic Variables | n | Low | High | P |
|---|---|---|---|---|
| (n = 117) | (n = 110) | |||
| Sex | ||||
| Female | 29 | 12(5%) | 17(7%) | 0.320 |
| Male | 198 | 105(46%) | 93(41%) | |
| Age, y | ||||
| ≤50 | 99 | 53(23%) | 46(20%) | 0.688 |
| >50 | 128 | 64(28%) | 64(28%) | |
| Preoperative AFP(ng/mL) | ||||
| ≤20 | 88 | 46(20%) | 42(19%) | 0.892 |
| >20 | 139 | 71(35%) | 68(30%) | |
| Liver cirrhosis | ||||
| No | 71 | 32(14%) | 39(17%) | 0.200 |
| Yes | 156 | 85(37%) | 71(32%) | |
| ALT(units/L) | ||||
| ≤75 | 158 | 74(32%) | 84(37%) | 0.274 |
| >75 | 69 | 33(15%) | 36(16%) | |
| Tumor size(cm) | ||||
| ≤5 | 143 | 81(36%) | 62(27%) | 0.168 |
| >5 | 84 | 39(17%) | 45(20%) | |
| Tumor number | ||||
| Single | 144 | 78(34%) | 66(29%) | 0.335 |
| Multiple | 83 | 39(17%) | 44(20%) | |
| Vein invasion | ||||
| No | 180 | 94(41%) | 86(38%) | 0.0028 |
| Yes | 47 | 36(16%) | 11(5%) | |
| TNM stage | ||||
| I–II | 138 | 58(25%) | 80(36%) | 0.0004 |
| III–IV | 89 | 59(26%) | 30(13%) | |
All analyses were conducted on 227 cases using χ2 tests. Median value of all 227 cases was chosen as the cut-off point for distinguishing miR-211 low-expression tumors from miR-211 high-expression cases.