Effect of s.c. administered 1400W (1 mg·kg−1 twice daily) for 7 days on IL‐1β expression in (A, A′) renal cortex, (B, B′) thoracic aorta and (C, C′) liver. The expression of IL‐1β was measured at the protein level by western blot (A, B, C) and at mRNA level by qRT‐PCR (A′, B′, C′). Data are mean ± SEM obtained from six rats per group. *P < 0.05 compared with control + vehicle; +P < 0.05 compared with glucose + vehicle; #P < 0.05 compared with control + 1400W.