Table 1. GO terms enriched with candidate genes for high-altitude adaptation in Tibetan sheep.

ID	Term	P value	P Bonferroni value	Associated genes
GO:0048667	cell morphogenesis involved in neuron differentiation	6.60E-05	0.0017	CHN1, CNP, EPHA8, FGFR2, NUMBL, OMG, SOD1, SPTBN4, TBR1
GO:0022829	wide pore channel activity	7.23E-05	0.0017	GJA3, GJB2, VDAC2
GO:0007409	axonogenesis	1.26E-04	0.0029	CHN1, CNP, EPHA8, FGFR2, NUMBL, OMG, SPTBN4, TBR1
GO:0016877	ligase activity, forming carbon-sulfur bonds	5.51E-04	0.0121	ACLY, ACSL6, SLC27A2
GO:0005681	spliceosomal complex	6.95E-04	0.0146	DHX38, HNRNPK, RALY, SMNDC1, TXNL4B, U2AF1
GO:0001666	response to hypoxia	2.71E-02	0.0271	EPAS1,CRYAA, LONP1
GO:0001894	tissue homeostasis	2.71E-02	0.0271	EPAS1, PTHLH, SOD1
GO:0048469	cell maturation	2.71E-02	0.0271	EPAS1, EPHA8, PPARG