Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 May 27;6:26883. doi: 10.1038/srep26883

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

Binding modes of approved sNRIs (A) atomoxetine (B) maprotiline (C) (S, S)-reboxetine and (D) viloxazine with hNET identified in this work. The ligands were displayed in cyan and hot spot residues were depicted in light pink. The salt bridge interaction was displayed in red dashed line and the hydrogen bond interaction was in green. Hot spot residues in subgroup A₁ (strong interaction) and A₂ (relatively strong interaction) shown in Fig. 5 were labeled in black and gray, respectively.