Skip to main content
. 2016 Apr 26;14(5):82. doi: 10.3390/md14050082

Table 3.

Cytotoxic activity of X. testudinaria extracts and isolated compounds 1.

Test Sample HeLa Cell HepG-2 Daoy
% Inhibition 2 IC50 3 % Inhibition 2 IC50 3 % Inhibition 2 IC50 3
EtOH extract 83.35 35.07 91.24 23.45 91.6 23.31
DCM + n-BuOH 36.45 NT 4 8.37 NT 4 36.45 NT 4
n-Hexane 91.28 33.7 89.31 30.2 90.5 20.74
1 35.78 NT 4 46.25 NT 4 34.07 NT 4
2 7.98 NT 4 14.72 NT 4 0 NT 4
5 4.17 NT 4 2.09 NT 4 0 NT 4
6 87.98 23.85 89.33 17.72 87.02 15.72
7 67 30.38 18.4 NT 4 77.56 23.1
9 58.61 44.41 45.23 NT 4 71.58 24.57
Dasatinib 56.4 16.22 89.67 6.91 90.36 9.2

1 Compounds 10–13 were evaluated before and were weakly cytotoxic, while 3, 4, and 8 were not tested due to lack of materials. 2 The percent of cell survival inhibition at 50 µg/mL, compared to control. 3 IC50s are expressed in (µg/mL). 4 NT: Not tested. HeLa: human cervical cancer; HepG-2: human hepatocellular carcinoma; Daoy: human medulloblastoma.