Table 1.

IC₅₀ values of compounds against A549 and HCT116 (MTT assay).

Compounds	A549 (nM ± SD) a	HCT116(nM ± SD) a
1a	2.2 ± 4.8	2.1 ± 0.4
1b	47.0 ± 9.9	2.3 ± 0.2
1c	35.0 ± 0.6	4.6 ± 0.7
1d	130.1 ± 48.3	25.5 ± 0.2
1e	19.5 ± 1.7	15.5 ± 1.8
1f	56.0 ± 3.3	3.7 ± 0.3
1g	41.5 ± 13.3	3.1 ± 0.8
1h	39.3 ± 2.4	8.3 ± 0.6
1i	8.7 ± 3.7	3.5 ± 0.9
TZT-1027	0.2 ± 0.06	0.3 ± 0.2
Docetaxel	23.5 ± 9.5	0.3 ± 0.1

^a The data were means from at least three independent experiments.