(A) Particle size distribution of plain chitosan-alginate microparticles of 1:1 ALG/CS mass ratio, prepared with chitosan of low molecular weight and alginates of decreasing G-content, according to Method (II) (solid) and Method (III) (dashed); (B) Zeta potential of plain chitosan-alginate microparticles of 1:1 ALG/CS mass ratio, prepared with chitosan of low molecular weight and alginates of decreasing G-content, according to Method (II) (□) and Method (III) (◌).The pH of alginate, chitosan and TPP solutions was initially set to 6.7, 4.1 and 9.0, respectively. Results are presented as mean ± SD (n = 3).