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. 2016 May 27;6:26597. doi: 10.1038/srep26597

Figure 6. Increased nrxn1 expression and reduced H3K36me2 at the nrxn1α promoter in the hippocampus of Ash1L (−/+) mice.

Figure 6

(A) Real-time PCR showed up-regulation of nrxn1α mRNA in the hippocampus of Ash1L (−/+) mice aged 3 months (n = 4 each group). (B) Samples from the hippocampus showed no changes in histone methylation levels in Ash1L (−/+) mice (full-length blots in Fig. S6; n = 3 each group). (C) ChIP was performed on the nrxn1α promoter using antibodies for H3K36me2, H3K4me3, H3R17me2 and H3K9ac in the hippocampus of wild-type and Ash1L (−/+) mice aged 3–4 months (n = 3). Student’s t-test, *P < 0.05.