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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: J Int Neuropsychol Soc. 2016 Jan;22(1):24–37. doi: 10.1017/S1355617715001101

Table 7. Positive (PPV) and negative (NPV) predictive values of CNT RCIs profiles by time (%).

24 hr Day 8 Day 15



PPV NPV PPV NPV PPV NPV
ANAM
 1+ decline 90.0 11.1 43.8 68.4 23.0 89.5
 2+ decline 100.0 14.9 12.6 37.9 7.9 75.6
Axon
 1+ decline 91.8 14.9 44.4 70.3 24.1 88.6
 2+ decline 100.0 16.9 18.0 31.7 21.3 85.8
ImPACT
 1+ decline 91.7 15.6 50.7 80.9 20.1 90.3
 2+ decline 95.4 13.9 16.3 53.0 39.1 88.7
Base rate of impairment 89.4 35.4 14.8

Note. Base rate = percentage of concussed athletes reporting being symptomatic at each assessment point. Given the outcome of interest involved predicting who from the concussed group was impaired from a symptom standpoint, sensitivities and specificity values were extracted from the symptomatic and symptom-free concussed athletes, respectively (which did not allow for computation at day 45 given the small sample of symptomatic subjects at this time point). 1+ (and 2+) decline reflects profiles with 1 or more (and 2 or more) RCIs demonstrated significantly worse performance as compared to an athletes' pre-injury baseline.

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