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. Author manuscript; available in PMC: 2016 May 27.
Published in final edited form as: Contrast Media Mol Imaging. 2012 Jan-Feb;7(1):26–34. doi: 10.1002/cmmi.460

Figure 8.

Figure 8

The dependence of CEST on temperature. (A) The percentage CEST effects of the amide (solid circles) and amine (open circles) of 30 mm of Yb–DO3A–oAA were measured at pH 7.30 using 10 µT saturation power over a range of temperatures. Linear fits of each CEST effect are shown as visual aids. (B) The pH values measured from the CEST effects of Yb–DO3A–oAA were strongly dependent on temperature (R2 = 0.94, 0.068 pH units per °C). (C) The dashed line represents the pH measured with an electrode and corrected for temperature effects.