Table 2. The significant associations of CLU loci with Aβ deposition in the whole group.
ROI | SNP | Baseline of the whole group |
|||
---|---|---|---|---|---|
Beta | Sample | P | FDR-P | ||
Frontal (SUVR) | rs11136000 | −0.039 | 574 | 0.023 | 0.052 |
rs1532278 | −0.037 | 574 | 0.030 | 0.052 | |
rs2279590 | −0.045 | 574 | 0.009 | 0.037 | |
rs7982 | −0.044 | 574 | 0.011 | 0.037 | |
Cingulate (SUVR) | rs1532278 | −0.039 | 574 | 0.033 | 0.079 |
rs2279590 | −0.051 | 574 | 0.005 | 0.035 | |
rs7982 | −0.044 | 574 | 0.018 | 0.063 | |
Parietal (SUVR) | rs7982 | −0.035 | 574 | 0.047 | 0.137 |
Temporal (SUVR) | rs2279590 | −0.032 | 574 | 0.041 | 0.183 |
Summary (SUVR) | rs11136000 | −0.032 | 574 | 0.009 | 0.030 |
rs1532278 | −0.029 | 574 | 0.023 | 0.039 | |
rs2279590 | −0.031 | 574 | 0.013 | 0.030 | |
rs7982 | −0.035 | 574 | 0.006 | 0.030 | |
rs9331888 | 0.021 | 572 | 0.018 | 0.042 |
ROI = regions of interest; SUVR = florbetapir standard uptake value ratios.
The blue color means the P value is still significant after FDR correction.