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. 2016 May 27;6:26745. doi: 10.1038/srep26745

Table 2. Relationships of cIMT and fasting TMAO levels with selected parameters at baseline.

  TMAO levels cIMT
r p r p
Age 0.23 0.0006 0.64 <0.0001
Body mass index 0.14 0.03 0.19 0.004
Total body fat MRT 0.07 0.27 0.06 0.42
Visceral fatMRT 0.12 0.07 0.40 <0.0001
Liver fatMRS 0.05 0.45 0.23 0.0005
Fasting glucose 0.15 0.02 0.25 0.0002
Fasting insulin 0.02 0.72 0.12 0.07
2 hr glucose −0.08 0.25 0.18 0.008
Total cholesterol 0.14 0.04 0.17 0.01
HDL-cholesterol 0.01 0.84 −0.12 0.08
LDL-cholesterol 0.14 0.03 0.12 0.005
Triglycerides 0.07 0.29 0.12 0.07
Apolipoprotein B 0.18 0.009 0.27 <0.0001
Hs-CRP −0.01 0.88 0.13 0.06
TNF-alpha* 0.27 0.001 0.10 0.22
Systolic BP 0.006 0.93 0.19 0.005
Diastolic BP −0.005 0.94 0.12 0.09
eGFR −0.14 0.04 −0.06 0.36
HOMA-IR 0.05 0.48 0.15 0.02
Insulin sensitivityOGTT −0.002 0.98 −0.18 0.009
Insulin sensitivityClamp# −0.03 0.75 −0.13 0.10
Insulin clearance 0.03 0.62 −0.11 0.12

r, Pearson correlation coefficient; *Only available in 144 subjects. #Only available in 167 subjects. BIA, body impedance; MRT, magnetic resonance tomography; MRS, magnetic resonance spectroscopy. MRT: magnetic resonance tomography, MRS: magnetic resonance spectroscopy; eGFR: estimated glomerular filtration rate; HOMA-IR: homeostatic model assessment of insulin resistance; cIMT: carotid intima-media thickness; TMAO: trimethylamine N-oxide; BP: blood pressure.