Table 4.
Changes in outcomes for blood lipids following 12 weeks weight loss (Week 12) and 12 weeks weight maintenance (Week 24).
| p Value | ||||||||
|---|---|---|---|---|---|---|---|---|
| Week 12 | Change * | Week 24 | Change ^ | Overall Change | Diet | Time | Group × Time | |
| Total cholesterol (mmol/L) | 0.93 | <0.001 | 0.049 | |||||
| HP | 4.1 ± 0.2 | −0.6 ± 0.1 | 4.3 ± 0.2 | 0.3 ± 0.1 | −0.4 ± 0.1 | |||
| HC | 4.2 ± 0.2 | −0.2 ± 0.1 | 4.4 ± 0.2 | 0.2 ± 0.1 | −0.03 ± 0.1 | |||
| LDL-C (mmol/L) § | 0.94 | 0.02 | 0.18 | |||||
| HP | 2.3 ± 0.2 | −0.3 ± 0.1 | 2.4 ± 0.2 | 0.02 ± 0.1 | −0.3 ± 0.1 | |||
| HC | 2.4 ± 0.2 | −0.1 ± 0.1 | 2.5 ± 0.2 | 0.1 ± 0.1 | −0.004 ± 0.1 | |||
| HDL-C (mmol/L) | 0.87 | 0.004 | 0.14 | |||||
| HP | 1.1 ± 0.05 | −0.05 ± 0.03 | 1.2 ± 0.05 | 0.1 ± 0.04 | 0.03 ± 0.03 | |||
| HC | 1.2 ± 0.05 | 0.02 ± 0.03 | 1.3 ± 0.06 | 0.1 0.04 | 0.1 ± 0.03 | |||
| Triglycerides (mmol/L) | 0.43 | <0.001 | 0.15 | |||||
| HP | 1.3 ± 0.1 | −0.8 ± 0.2 | 1.6 ± 0.2 | 0.3 ± 0.2 | −0.4 ± 0.2 | |||
| HC | 1.5 ± 0.1 | −0.5 ± 0.2 | 1.5 ± 0.2 | −0.03 ± 0.2 | −0.6 ± 0.2 | |||
Data is represented by means ± SEM for the 61 participants who commenced the study. HP: higher-protein diet (n = 32); HC: higher-carbohydrate diet (n = 29). *: Change from baseline, ^ Change from phase 1; §: LDL cholesterol could not be calculated for five participants at baseline (HP n = 29, HC n = 27) due to triglycerides levels > 4.2 mmol/L. Abbreviations: HDL-C, high-density lipoproteins; LDL-C, low-density lipoprotein cholesterol.