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. 2016 May 26;17:407. doi: 10.1186/s12864-016-2711-5

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© Fleming et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Statistically significant SNPs annotated to PRKCA fall within an intronic region of the gene near a cysteine-rich domain superfamily [86]. Variants are located near the protein kinase cysteine-rich domain, a group of small proteins that have functions possibly involved in the response to environmental stressors