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. 2016 May 27;16:27. doi: 10.1186/s12902-016-0106-x

Table 1.

Association between metabolic syndrome and a recent history of osteoporotic fracture

Men Women
OR (95 % CI) P value OR (95 % CI) P value
unadjusted 1.08 (0.70–1.68) 0.737 1.38 (1.04–1.85) 0.028
Model 1 0.96 (0.73–1.57) 0.596 1.25 (1.02–1.69) 0.031
Model 2 0.87 (0.68–1.44) 0.264 1.20 (1.02–1.57) 0.034
Model 3 1.00 (0.74–1.36) 0.986 1.23 (1.09–1.45) 0.038
Model 4 1.00 (0.73–1.36) 0.991 1.21 (1.11–1.42) 0.038
Model 5 1.01 (0.75–1.61) 0.784 1.18 (1.13–1.39) 0.039
Model 6 1.20 (1.11–1.53) 0.040

We defined participants without osteoporotic fractures as 0 and those with osteoporotic fractures as 1. Model 1 was adjusted for age, smoking and alcohol consumption habits (yes/no), physical activity (MET-h/wk), and eGFR. Model 2 was further adjusted for BMI, waist circumference and hip circumference based on model 1. Model 3 was further adjusted for serum TG, TC, HDL-c, and LDL-c based on model 2. Model 4 was further adjusted for diabetes status (yes/no), FPG and HbA1c based on model 3. Model5 was further adjusted for blood pressure on model 4. Model 6 was further adjusted for menopause status (yes/no) and hormone replacement (yes/no) treatment for women based on model 5