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MUC1-C promotes MYC-driven transcriptional programs. (A-B) Gene expression profiling of MYC family members and MYC-dependent genes in (A) RPMI8226/WT and RPMI8226/CRISPR cells and (B) U266/WT and U266/CRISPR cells. The change in gene expression was calculated using the ΔΔCt method. (C-E) The results of arrays were confirmed for protein expression of (C) CCND2 (cyclin D2), (D) hTERT, and (E) GCLC by immunoblotting.
