Table 2.
Hazard ratios (HR), 95 % confidence intervals (CI) and p values for breast and endometrial cancer analysis in relation to EIG121 STR lengths
| Category | Statistical test | Breast cancer | Endometrial cancer | ||
|---|---|---|---|---|---|
| HR (95 % CI) | p value | HR (95 % CI) | p value | ||
| Both allele lengths with cancer risk | Mann–Whitney U test | N/A | 0.985 | N/A | 0.262 |
| Both allele lengths with age at diagnosis | Cox proportional hazard regression | 0.994 (0.981–1.007) | 0.343 | 1.006 (0.995–1.017) | 0.304 |
| Both allele lengths with age at diagnosis (BMI considered) | Cox proportional hazard regression | N/A | N/A | 1.003 (0.992–1.015) | 0.572 |
| Allelic analysis (S/L) | Pearson’s Chi squared test | N/A | 0.185 | N/A | 0.393 |
| Genotypic analysis (SS/SL/LL) | Fisher’s exact test | N/A | 0.102 | N/A | 0.545 |