Table 5.
Results of SIFT predictions of non-synonymous SNPs
| SNP | Substitution | dbSNP | Score | Prediction |
|---|---|---|---|---|
| 31G > A | Val11Met | rs769258 | 0.12 | TOLERATED |
| 100C > T | Pro34Ser | rs1065852 | 0.00 | AFFECT PROTEIN FUNTION |
| 973C > A | Leu91Met | rs28371703 | 0.01 | AFFECT PROTEIN FUNTION |
| 983A > G | His94Arg | rs28371704 | 0.35 | TOLERATED |
| 1673G > A | Arg140His | novel | 0.00 | AFFECT PROTEIN FUNTION |
| 2467 T > C | Leu231Pro | novel | 0.11 | TOLERATED |
| 2607G > A | Glu278Lys | novel | 0.06 | TOLERATED |
| 2611 T > A | Met279Lys | rs201830078 | 0.00 | AFFECT PROTEIN FUNTION |
| 3854G > A | Glu410Lys | rs769157652 | 0.14 | TOLERATED |
| 4181G > C | Ser486Thr | rs1135840 | 0.37 | TOLERATED |