Table 1.

Selection of the best estimate of the distance from the centromere where aligned chromosome arms become separated.

Ranges of distances	# Rearr.	Hi-C contact freq.		|X − Y|
		P-value	Fold change	P-value	Fold change
0–200Kb and 200–400Kb	44 and 10	0.023	2.27	0.11	1.30
0–225Kb and 225–450Kb	46 and 11	0.016	2.29	0.0085	1.59
0–250Kb and 250–500Kb	49 and 11	0.036	2.14	0.0051	1.72
0–275Kb and 275–550Kb	57 and 9	0.12	2.00	0.11	1.21
0–300Kb and 300–600Kb	64 and 9	0.37	1.65	0.051	1.52

Note: Wilcoxon test p-values and fold changes of average spatial distances were calculated between two ranges of distances from the rearrangement event to the centromere. Spatial distance between genes X and Y with a predicted rearrangement event was measured as Hi-C contact frequency or |X − Y| estimated via the linear distance to the centromere.