Fig. 10.
Electrophoresis mobility shift assays for cisplatin and compounds [(η5-C5H5)TiCl3], [(η5-C5H5)2TiCl2], a·HCl-c·HCl, 1a·HCl-1c·HCl and 2a–2c (see Experimental Section for details). DNA refers to untreated plasmid pBR322. Lanes a, b, c and d correspond to metal/DNAbp ratios of 0.25, 0.5, 1.0 and 2.0 respectively. OC open circular or relaxed form (Form II), CCC covalently closed or supercoiled form, (Form I).
