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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: J Inorg Biochem. 2015 Dec 9;156:22–34. doi: 10.1016/j.jinorgbio.2015.12.002

Table 2.

IC50 values (μM) ± S.E.M.a in human cell lines were determined with 2b and 2c. Reported values for cisplatin, [(η5-C5H5)2TiCl2], and Titanocene Y are indicated for some cell lines.

Compound Caki-1 DLD-1 MDA-MB-231 HEK-293T
2b 8.55 ± 2.77 59.66 ± 4.97 > 100 50.99 ± 7.15
2c 4.51 ± 1.17 44.09 ± 3.10 > 100 70.22 ± 11.22
[(η-C5H5)2TiCl2]b > 200 ---- --- > 200
Titanocene Yb 29.42 ± 4.18 --- --- > 200
Cisplatinb 29 ± 4.11 --- --- 3.27 ± 0.13
a

Each value represents the mean ± S.E.M. of at least two independent experiments.

b

Values obtained with the same technique, cell lines and incubation times [27,30].