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Invasion of engineered B16F10 MCC: Reduced invasion of CD146-silenced MCC to craniofacial, appendicular structures and liver (compared to NT-shRNA), evaluated by BLI (a) and gross examination (b and c). BLI signal reached statistical significance (* = p < 0.01). Data are represented as mean ± SEM. Representative mice of n = 6 (3 per group).
