Figure 6.

miR‐98 inhibits RAOEC growth. (A) MTT analysis results showing that the inhibition rate of cell proliferation was much higher in miR‐98‐treated endothelial cells compared with NC‐oligo‐treated cultures, and antisense RNA (ASO‐98) reduced the role of miR‐98 in suppression of cell growth. *P < 0.01, miR‐98 treatment versus NC‐control treatment or ASO‐98 treatment, n = 3 replicates. (B) Flow cytometry results showing that miR‐98 treatment induced G1 phase inhibition compared with control treatment. (C) Cell apoptosis. The apoptotic cell rate was 23.7% in miR‐98‐treated cells, which was much higher than that in NC‐ (4.4%) or ASO‐98‐treated cells (6.2%), n = 3 replicates.