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. Author manuscript; available in PMC: 2016 May 27.
Published in final edited form as: Photochem Photobiol. 2014 Oct 13;91(1):235–241. doi: 10.1111/php.12351

Figure 3.

Figure 3

Interleukin-17 regulates the development of UVR-induced CD4+ regulatory T cells. Wild-type and IL-17R−/− mice were irradiated with UVB (200 mJ cm−2) on shaved back skin once a day for four consecutive days (Wt/UV and Ko/UV). The mice were sensitized once with DNFB on the UVR-treated skin area 24 h after the last UVR. Control mice which were not treated with UVR (Wt/Ctrl and Ko/Ctrl) were also sensitized with DNFB. Spleen and the draining lymph node cells from all sensitized mice were harvested 5 days later. CD4+ T cells were purified and transferred i.v. into naïve wild-type mice (5 × 106 cells/mouse), which were not treated with UVR. The recipient mice were sensitized with DNFB 24 h later and challenged 5 days after the sensitization. Data show mean ± SE (5 mice/group) of one of two independent experiments, *P < 0.05.