Figure 1.

Histological illustration of rat heart sections stained with H and E, ×400. (a) Control: Normal cardiac architecture, showing no lesions or abnormalities; (b) CdCl2 (cadmium alone): Cardiac fiber degeneration characterized by extensive edema and infiltration of inflammatory cells; (c) CdT1 (200 mg/kg body weight): Illustration of mild mononuclear cellular infiltration; (d) CdT2 (400 mg/kg body weight): Edema and mononuclear cellular infiltration were hardly detected, illustrating improved cardiac architecture. Arrows in B and C indicate the regions with pronounced damage in cadmium-challenged rat heart