Table 4.
Monthly total healthcare cost and cost by settings during the 6-month pre-index and 12-month post-index periods of commercially insured acromegalic individuals, by study cohort
| 6-month pre-index period | 12-month post-index period | |||||
|---|---|---|---|---|---|---|
| Medical therapy (N = 169) | Surgical therapy (N = 228) | p value | Medical therapy (N = 169) | Surgical therapy (N = 228) | p value | |
| Total healthcare cost per month | 2818.4 (5714.8) | 1963.5 (4253.7) | 0.009 | 3076.5 (3723.7) | 5202.6 (3423.0) | <0.001 |
| % of total healthcare cost attributable to acromegaly-associated total healthcare cost | NA | NA | 56.0 | 52.5 | ||
| Cost of inpatient stays per month | 847.4 (4803.5) | 750.1 (3321.6) | 0.739 | 347.7 (1332.0) | 2807.7 (2021.1) | <0.001 |
| % of inpatient cost attributable to acromegaly-associated inpatient cost | NA | NA | 25.8 | 72.5 | ||
| Cost of outpatient care per month | 929.6 (2683.4) | 1038.1 (1685.3) | <0.001 | 1366.6 (2829.3) | 1938.1 (2201.6) | <0.001 |
| % of outpatient cost attributable to acromegaly-associated outpatient cost | NA | NA | 33.3 | 21.8 | ||
| Pharmacy costs per month | 1041.5 (1561.0) | 175.3 (405.8) | <0.001 | 1362.3 (1692.7) | 456.9 (788.9) | <0.001 |
| % of pharmacy cost attributable to acromegaly-associated pharmacy cost | NA | NA | 86.6 | 59.3 | ||
Data are presented as mean (standard deviation) unless otherwise indicated; costs are presented as $US
Statistical comparisons of cost were made using the Wilcoxon rank-sum test
NA not available