Table 4.

Mean ± SD main pharmacokinetic parameters of the test and reference formulations (n = 20)

Pharmacokinetic parameters	Reference formulation (mean ± SD)	Test formulation (mean ± SD)	90% Confidence limit (%)
T max (h)	3.65 ± 1.14	3.85 ± 1.04
C max (ng/ml)	34.3 ± 9.5	44.1 ± 27.6	103.8–142.3
AUC0–60d (ng h/ml)	1679 ± 385	1789 ± 383	100–114.2
AUC0–∞ (ng h/ml)	1819 ± 417	1950 ± 435	100–115.5
t 1/2 (h)	272 ± 76	298 ± 105

Reference formulation: Shanghai Zhongxi Pharmaceutical Co., Ltd., Shanghai, China

Test formulation: Jiangsu Shenhua Pharmaceutical Co., Ltd., Jiangsu, China