Fig. 1.

Distribution of FN (a) and EDA-FN (b) concentrations in plasma of patients with atherosclerosis. pFN (a) and EDA-FN (b) concentrations were determined by ELISA [35], using two monoclonal antibodies domain-specific directed to cell-binding domain of FN (FN30-8; M010 TaKaRa Shuzo Co. Ltd., Shiga, Japan) and EDA segment of FN (EMD Millipore, Merck KGaA Darmstadt, Germany). For details see “Materials and Methods.” Data are given as mean values ± SD, median, and (25th and 75th) quartiles. Significantly different from the age-matched normal group calculated by the Kruskal–Wallis and post hoc tests.