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Different types of ECM scaffolds available to use for tissue engineering applications: (a) natural ECM, for example, collagen; (b) other biomaterials, for example, fibrin, silk (typically in the form of electrospun fibres or as a coating on a 2D substrate); (c) decellularised ECM (stripped of all previous cellular material) and (d) synthetic ECM, for example, polymers (usually in fibres or hydrogels) adapted from Brafman.128
ECM: extracellular matrix; 2D: two-dimensional.
