Table 1. Participant Characteristics.
| Varenicline (N = 760) | Placebo (N = 750) | |
|---|---|---|
| Demographic Characteristics | ||
| Sex, n (%) | ||
| Male | 425 (55.9) | 426 (56.8) |
| Female | 335 (44.1) | 324 (43.2) |
| Age, years | ||
| Mean (SD) | 44.7 (11.8) | 44.4 (12.0) |
| Range | 19-79 | 18-78 |
| Race, n (%) | ||
| White | 476 (62.6) | 463 (61.7) |
| Black | 36 (4.7) | 47 (6.3) |
| Asian | 175 (23.0) | 177 (23.6) |
| Other | 73 (9.6) | 63 (8.4) |
| Smoking Characteristics | ||
| Fagerström Test for Cigarette Dependencea, mean (SD) | 5.5 (2.1) | 5.6 (2.0) |
| Age started smoking, years, mean (SD) | 17.3 (4.3) | 17.3 (4.4) |
| Number of cigarettes per day in past month, mean (SD) | 20.6 (8.5) | 20.8 (8.2) |
| Longest period of abstinence, days | ||
| Since started smokingMedian (25th, 75th percentile) | 30 (3, 240)272 | 21 (2, 180)206 |
| Mean | ||
| In past year | 0 (0, 0) | 0 (0, 1) |
| Median (25th, 75th percentile) | 4 | 3 |
| Mean | ||
| Number of serious quit attempts by any method, n (%) | ||
| Since started smoking | ||
| None | 130 (17.1) | 159 (21.2) |
| One | 191 (25.1) | 188 (25.1) |
| Two | 139 (18.3) | 110 (14.7) |
| Three or more | 300 (39.5) | 293 (39.1) |
a
Fagerström Test for Cigarette Dependence measures degree of cigarette dependence with scores ranging from 0 to 10 with higher scores indicating a higher degree of dependence.17
Abbreviations: N = all randomized participants; n = number of participants with the given characteristic; SD = standard deviation.