Table 3.

In Vitro Antimicrobial Activity of the Isolated Glycosides

	MRSA		S. aureus
compound	IC50a	MICb	IC50a	MICb
1	2.0	10	3.7	13.3
2	0.8	1.7	1.6	5.8
3	0.7	1.3	1.4	3.8
4	0.4	0.6	1.6	2.5
methicillin	NA	NA	0.4	2.5
piperacillin	NA	NA	NT	NT
cloxacillin	8.9	NA	NT	NT
ciprofloxacin	0.1	0.3	0.1	0.4

^aIC₅₀ = the concentration that affords 50% inhibition of growth (µg/mL).

^bMIC (minimum inhibitory concentration, µg/mL) is the lowest test concentration that allows no detectable growth.

^cMBC (minimum bactericidal concentration) is the lowest test concentration that kills the organism (µg/mL).

^dNA = not active at the highest test concentration.

^eNT = not tested.