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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: J Cell Biochem. 2015 Oct 6;117(4):959–969. doi: 10.1002/jcb.25380

Table 1.

Trabecular bone; MicroCT analysis of distal femurs and static histomorphometric analysis, 20-week old c-Mpl−/− and WT mice

MicroCT Histology
Mice n BV/TV (%) SMI Tb.Th (mm) Tb.N
(1/mm)		 Tb.Sp (mm) n BV/TV
(%)		 N.Ob/
TAR		 N.Oc/
TAR		 BFR/TV
(µm2/µm3/year)		 MAR
(µm/day)
C57BL/6 (WT) 38 3.6 ± 0.3 2.69 ± 0.05 0.053 ± 0.002 0.69 ± 0.05 0.34 ±0 .01 11 3.9 ±0 .8 59 ± 13 29 ± 4 317 ± 43 1.7 ±0 .2
c-Mpl−/− 27 12.4 ± 0.6* 2.00 ± 0.05* 0.048 ± 0.001 2.6 ± 0.1* 0.19 ±0 .01* 10 8.4 ± 1.1* 97 ± 13* 58 ± 8* 354 ± 22 1.9 ±0 .1

BV/TV, bone volume/total volume; SMI, structure model index; Tb.Th, trabecular thickness; Tb.N, trabecular number; Tb.Sp, trabecular separation; BV/TV, bone volume/total volume; N.Ob/TAR, number of osteoblasts/tissue area; N.Oc/TAR, number of osteoclasts/tissue area; BFR/TV, bone formation rate/tissue volume; MAR, mineral apposition rate.

Results are presented as mean ± SEM;

*

Indicates significant difference compared to WT (p<0.05)