Table 2.
Anthropometrics, cortical bone histomorphometry properties, 20-week old c-Mpl−/− and WT mice
| Anthropometrics | Cortical Bone Histomorphometry | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Mice | n | Length (µm) |
Width (µm) | Height (µm) | n | CSA (µm2) | BA (µm2) | Periosteal BFR (µm2/µm3/day) |
Endocortical BFR (µm2/µm3/day) |
| C57BL/6 (WT) | 37 | 15.3 ± 0.1 | 1.74 ± 0.03 | 1.29 ± 0.02 | 19 | 1.72 ±0 .04 | 0.86 ± 0.05 | 17 ± 4 | 53 ± 2 |
| c-Mpl−/− | 26 | 15.0 ± 0 .1 | 1.76 ± 0 .03 | 1.26 ± 0.02 | 10 | 1.74 ±0 .05 | 0.72 ±0 .02* | 17 ± 4 | 33 ± 5* |
Length, distal to proximal femur length; Width, medial to lateral femur width; Height, ventral to dorsal femur height; CSA, cross-sectional area; BA, bone area; Periosteal BFR, periosteal bone formation rate; Endocortical BFR, endocortical bone formation rate.
Results are presented as mean ± SEM;
Indicates significant difference compared with gender matched WT (p<0.05)