Table 1. References for the investigated crosstalk interactions in the PDGF signalling network.

Crosstalk number	Descriptions	References
1	Ras -> PI3K	[34]
2	MEK1,2 -| Grb2SOS	[35]
3	PI3K -> Ras	[3]
4	PI3K -> MEK1,2	[5]
5	PIP3 -> GabSOS	[36]
6	Akt -| GabSOS	[37]
7	Akt -| Raf	[4]
8	PLCγ -> PI3K	[38]
9	PKC -> MEK1,2	[5]

The crosstalk interactions among MAPK, PI3K/AKT/mTOR and PLCγ/PKC pathways within PDGF signalling as suggested by literature are listed. The annotation ‘->‘ refers to activation and the annotation ‘-|’ refers to inhibition.