Table 2.
Lung function values of subjects S10 to S13 and P1 to P2
| Subject | FEV1 (% pred) | FVC (% pred) | FEV1/FVC (% pred) | TLC (% pred) | RV (%pred) | RV/TLC (%pred) | DLCOc (%pred) | Significant (≥12%) change of FEV1 after bronchodilator | AUC(CV > 20%) [%] |
|---|---|---|---|---|---|---|---|---|---|
| S10 | 125 | 119 | 107 | - | - | - | 85 | No | 39 |
| S11 | 114 | 114 | 102 | 103 | 96 | 93 | 95 | No | 41 |
| S12 | 89 | 91 | 98 | 106 | 128 | 120 | 76 | No | 47 |
| S13 | 91 | 94 | 98 | - | - | - | - | - | 47 |
| P1 | 79 | 107 | 74 | - | - | - | 85 | Yes | 43 |
| P2 | 40 | 57 | 72 | 132 | 214 | 165 | 38 | No | 61 |
Subjects with AUC(CV > 20%) values of more than 37%. Subjects S10 to S13 are listed in order of increasing AUC(CV > 20%) value. FEV1, forced expiratory volume over one second; FVC, forced vital capacity; TLC, total lung capacity; RV, residual volume; DLCOc, single breath dilution carbon monoxide test adjusted for haemoglobin concentration in the blood. Lung function values without bronchodilator use are reported as percentage of predicted reference values (% pred).