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Differential expression of VEGFR-1 and VEGFR-2 on endothelial cells and macrophages. Double immunofluorescent staining for VEGFRs and markers of endothelial cells (FVIII) and macrophages (Mac-3). Serial atherosclerotic sections from diabetic mice were double-stained for VEGFR-1 and Mac-3 (upper row) or VEGFR-2 and FVIII (lower row), as indicated. Co-localization is visible on merged images as the yellow color.
