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. Author manuscript; available in PMC: 2016 May 27.
Published in final edited form as: Neuroscience. 2013 Oct 21;256:467–477. doi: 10.1016/j.neuroscience.2013.10.025

Fig. 3.

Fig. 3

Effect of THDOC on Ictal-like events. (A) Representative examples of ictal discharges in the 4AP control condition, 4AP+0.1 μM THDOC and the 4AP +5 μM THDOC condition. (B) Bar graph showing the average duration of ictal discharges following the application of 4AP and THDOC. THDOC induced a significant decrease in ictal discharge duration compared to 4AP in both the anterior and posterior regions of the piriform cortex. (C) Number of ictal discharges per hour following in the 4AP control condition, 4AP+0.1 μM THDOC and 4AP+0.5 μM. The frequency of ictal discharges did not change significantly following the application of THDOC. (*p<0.05 4AP pooled data n=13, 0.1 μM THDOC n=7, 5 μM THDOC n=7).