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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Neuropharmacology. 2015 Apr 29;95:377–387. doi: 10.1016/j.neuropharm.2015.04.015

Fig. 5.

Fig. 5

A: Field potential recordings obtained from PC and EC areas during application of 4AP (50 μM), PTX (100 μM) and ACTZ (10 μM, n = 6 experiments). Note that PTX abolishes long-lasting ictal discharges in both brain regions whereas interictal discharges continue to occur. Enlarged portion of the recordings during 4AP + PTX and 4AP + PTX + ACTZ are shown in insets. B: Bar graphs showing the average duration of ictal and interictal discharges recorded from the PC and EC in 4AP + PTX and during 4AP + PTX + ACTZ application. C: Bar graphs showing the average interval of occurrence of ictal and interictal discharges recorded from PC and EC during 4AP + PTX and 4AP + PTX + ACTZ. Note that further application of ACTZ (10 μM) does not affect neither the duration and nor the interval of epileptiform events.