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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Neuropharmacology. 2015 Apr 29;95:377–387. doi: 10.1016/j.neuropharm.2015.04.015

Fig. 7.

Fig. 7

A: Rate of occurrence of ripples and fast ripples during ictal discharges recorded from the PC and the EC during control (4AP, 10 μM) and during application of ACTZ (10 μM, n = 10 experiments). The duration of the ictal discharges was normalized from 0 (start of the ictal discharge) to 100 (end of the ictal discharge) to account for different durations. Note that in both PC and EC, the rates of occurrence of ripples and fast ripples throughout the ictal discharges are reduced by ACTZ (10 μM). B: Bar graphs showing the proportion of interictal discharge co-occurring with ripples and fast ripples in PC and EC under control conditions and in the presence of ACTZ (10 μM). Note that in both regions the percentage of interictal discharges co-occurring with fast ripples is reduced by ACTZ (10 μM). *p < 0.05, **p < 0.001.