Figure 4.

Renal cells expressing EPC surface makers are not bone marrow derived. Most bone marrow (A) and blood cells (B) of chimeric mice (D: tdT+; R: C57BL/6) mice were positive for tdT (donor derived). Significantly more tdT+ cells were recruited to the kidney (C). Cells expressing ECFC surface markers (D, left) were negative for tdT (D, right). Selective EC injury was accompanied by a significant inflammatory response as depicted by influx of neutrophils (E), macrophages (F), dendritic cells (G), CD4+ T cells (H), CD8+ T cells (I), and HSC (J).