Intrarenal administration of ELP-VEGF improved renal function, and cortical and medullary vascular density in the stenotic kidney. Effect of intrarenal ELP-VEGF on renal function (top) and MV architecture (three-dimensional micro-CT reconstruction, bottom) and quantification in normal, RVD-, RVD+ELP-, and RVD+ELP-VEGF–treated kidneys. *P<0.05 versus Normal; †P<0.05 versus RVD/RVD+ELP; ‡P<0.05 versus 6 weeks. (B) Cortical and medullary quantification of MV density divided by MV diameter in normal, RVD-, and RVD+ELP-VEGF–treated kidneys. *P<0.05 versus Normal; †P<0.05 versus RVD.