Table 1.
Baseline characteristics and data regarding common carotid artery, aortic dimensions, and arterial PWVs
| Variable | Controls(n=73) | ESRD(n=156) | P Value |
|---|---|---|---|
| Age (yr) | 53±1.8 | 54±1.25 | NS |
| Sex (men/women) | 43/30 | 88/48 | NS |
| Body surface area (m2) | 1.87±0.03 | 1.71±0.02 | <0.001 |
| Body height (m) | 1.70±0.02 | 1.65±0.1 | <0.001 |
| Brachial systolic BP (mmHg) | 145±2.6 | 150±2.4 | NS |
| Brachial diastolic BP (mmHg) | 84±1.8 | 81±1.2 | NS |
| Brachial mean BP (mmHg) | 105±1.9 | 104±1.4 | NS |
| Common carotid artery systolic BP (mmHg) | 135±1.8 | 143±2.1 | <0.01 |
| Common carotid artery pulse pressure (mmHg) | 51±2.2 | 62±2.0 | <0.001 |
| Common carotid artery augmentation index (%) | 19±1.4 | 27±1.1 | <0.001 |
| Common carotid artery augmented pressure (mmHg) | 11±1.2 | 18±1.1 | <0.001 |
| Common carotid artery forward pressure (mmHg) | 39±1.2 | 44±1.1 | 0.01 |
| Left ventricular ejection time (ms) | 309±3.0 | 309±3.0 | NS |
| Diastolic time (ms) | 666±17 | 585±10 | <0.001 |
| Aortic PWV (m/s) | 9.6±0.2 | 11.1±0.2 | <0.001 |
| Brachial PWV (m/s) | 11.0±0.2 | 11.4±0.2 | 0.03 |
| Femoral PWV (m/s) | 10.9±0.2 | 11.3±0.1 | 0.03 |
| Brachial/aortic stiffness gradient | 1.08±0.01 | 1.03±0.01 | <0.001 |
| Femoral/aortic stiffness gradient | 1.07±0.01 | 1.03±0.01 | <0.01 |
| Ascending aortic diameter (mm)a | 28.2±0.3 | 27.8±0.3 | NS |
| Aortic bifurcation diameter (mm)b | 16.4±0.2 | 17.7±0.3 | <0.001 |
| Aortic taper (ascending aortic diameter/aortic bifurcation diameter) | 1.72±0.15 | 1.60±0.25 | <0.001 |
Values are means±SEMs.
a
Ascending aortic diameter (millimeters per meter2): controls: 14.9±1.6 versus ESRD: 16.5±2.10 (P<0.001).
b
Aortic bifurcation diameter (millimeters per meter2): controls: 8.8±1.4 versus ESRD: 10.5±1.6 (P<0.001).